What is the test method?

Our food intolerance tests are done using a blood based method covering IgG 1,2,3,4, the blood sample collection process is done via a pin prick to the finger, it takes around 4-5 large droplets.

Why do food cause an IgGantibodies response?

Generally, foods are broken down during digestion into their component parts e.g. amino acids, glycerides etc. These pass harmlessly through the gut as the gut becomes inflamed (bloated) these proteins enter the bloodstream. This is where they are recognized by the immune system as being ‘foreign’. The immune system responds by making IgG antibodies to these foods.

What is the difference between hair and blood based test?

You can't test immune reactions via a hair sample, and in many cases there have been discrepancies in results when parts of the hair have been coloured/bleached. This has led to inconsistency in the sample tested twice. Our IgG 1,2,3,4 blood based testing covers the full range of antibodies responses, this is important, if a particular food elevates any antibodies against it, this means your gut and immune system recognises that food as a threat. This could affect the nutrients absorbed from this particular food and leads to multiple symptoms.

Do high IgG antibody levels cause symptoms?

When a food causes the body to produce high levels of IgG then these antibodies combine with the protein in the food to form an ‘antigen-antibody complex’. These complexes are usually eliminated by other cells in the immune system. However, if the immune system is overloaded, these insoluble molecules become deposited in tissues within the body, causing chronic inflammation and the subsequent production of symptoms.

Why test for IgG antibodies to foods?

The efficacy of a diet based on the measurement of IgG antibodies specific for food components has been demonstrated in a number of conditions, both in independent studies and clinical practice. Excellent results have been obtained in patients with migraine, IBS and obesity.

What is the lower age limit for testing?

Supply Life's existing policy for a lower age limit on testing for IgG food antibodies is that we do not recommend testing on children under the age of 2 years. We base this on the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease 2012, which states that there is a possibility of false negative results occurring in infants younger than 2 years of age. This related to the fact that the infant gut is more permeable than that of an adult coupled with immature mucosal immunity that is still in the learning and development stage. We have used this criterion as antibody measurements in Coeliac Disease are comparable to food IgG measurements used in our food intolerance tests. However, we are aware that there are in fact no published guidelines that specifically indicate a minimum age for testing for such IgG antibodies, for example the guidelines for testing for coeliac antibodies indicate that such testing can be performed any time after the introduction of gluten into the diet. Therefore, where such requests are received from a statutory regulated professional the decision of when and what tests to perform will remain the responsibility of the requesting clinician.

What should be considered before testing - Is there any medication that I should avoid when taking a food intolerance test, due to its potential effects upon the results?

Customers should avoid the use of immunosuppressant medication if possible if performing these tests, as they may have an impact upon the results. Please refer to the medication datasheet in the “Support” section for further details.

How does the test work?

Food extracts are 'printed' onto nitrocellulose 'pads'™ on a glass microscope slide, together with calibration standards and controls. A blood sample provided by the patient is diluted and dispensed onto each printed microarray. Food IgG antibodies, if present, bind to the food extracts and the results are measured by a high-resolution scanner, before being calibrated against the standards using the reporting software to give quantitative results. This software then produces a tailor-made printout of the final food IgG antibody result for each food on the requested food panel.

Do you need to full the microvette all the way to the white line?

Although it is advisable to completely fill the tube, a half filled microvette tube should be enough to run the test. If there are any problems with a sample and the lab will let the customer know. However, if you are ordering two tests we can test from one sample if you provide a full microvette.

Do you need to store the blood in the fridge, if not sending the same day?

Yes, it does need to be stored in the fridge with the lid secured if not sending on the same day.

Can I upgrade my test to a larger food panel?

You can upgrade for up to a maximum of 4 weeks from the date that your first sample is received.

What are the sample requirements and test turnaround?

A pin-prick blood sample is required. Results are available within 10 working days.

Does the Supply Life test for all subclasses of IgG antibody or only IgG4?

Our process screens for all IgG subclasses 1-4, with the numbers on the test report representing the total IgG concentration for each food extract in the selected panel.

Fructose intolerance: Signs, Triggers and Advice

May 16, 2023

Fructose intolerance is a relatively common but often misunderstood condition that affects a significant number of individuals in the United Kingdom. This article aims to shed light on what fructose intolerance is, its prevalence, symptoms, potential dangers of ignoring food intolerances, and offer helpful tips for those suspecting they may have fructose intolerance.

If you suspect you might be experiencing fructose intolerance, investing in a home food intolerance test with Supply Life can provide valuable insights to manage your condition effectively.

What is Fructose Intolerance?

Fructose intolerance, also known as fructose malabsorption or dietary fructose intolerance, is a condition in which the body has difficulty digesting and absorbing fructose, a type of sugar found in various fruits, vegetables, and sweeteners. People with fructose intolerance lack the necessary enzymes to break down fructose effectively, leading to digestive issues and discomfort.

Prevalence of Fructose Intolerance in the UK

While exact numbers are challenging to determine, research suggests that fructose intolerance is more prevalent than previously believed, affecting a substantial portion of the UK population.

It is estimated that approximately 30% of the UK population may experience some degree of fructose intolerance, making it a significant health concern.

Symptoms of Fructose Intolerance

Fructose intolerance manifests through various symptoms, which may vary in intensity from person to person. Common symptoms include bloating, abdominal pain, excessive gas, diarrhoea, nausea, and general digestive discomfort. In some cases, individuals may also experience fatigue, headaches, and mood disturbances. If left unaddressed, fructose intolerance can significantly impact one's quality of life.

Dangers of Ignoring Food Intolerances

Neglecting to address fructose intolerance or any other food intolerance can have detrimental effects on an individual's overall health and well-being. Untreated fructose intolerance can lead to chronic digestive problems, nutrient deficiencies, weight loss or gain, reduced immune function, and even psychological distress. Identifying and managing food intolerances is crucial for maintaining optimal health.

Tips for Managing Fructose Intolerance

If you suspect you have fructose intolerance, it is essential to take proactive steps to manage your condition. Here are some helpful tips:

Keep a food diary: Monitor your diet and symptoms to identify potential trigger foods or patterns.
Educate yourself: Learn about fructose-containing foods and their alternative options.
Try an elimination diet: Temporarily eliminate high-fructose foods from your diet to assess symptom improvement.
Consider a food intolerance test: Home food intolerance tests, such as those offered by Supply Life, can provide valuable insights into your dietary sensitivities.

Invest in a Home Food Intolerance Test with Supply Life

If you suspect fructose intolerance or any other food intolerance, investing in a home food intolerance test with Supply Life can be an excellent step towards understanding your body's unique needs. Supply Life offers comprehensive, reliable, and easy-to-use testing kits, allowing you to identify potential food triggers and make informed dietary choices.

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