What is the test method?

Our food intolerance tests are done using a blood based method covering IgG 1,2,3,4, the blood sample collection process is done via a pin prick to the finger, it takes around 4-5 large droplets.

Why do food cause an IgGantibodies response?

Generally, foods are broken down during digestion into their component parts e.g. amino acids, glycerides etc. These pass harmlessly through the gut as the gut becomes inflamed (bloated) these proteins enter the bloodstream. This is where they are recognized by the immune system as being ‘foreign’. The immune system responds by making IgG antibodies to these foods.

What is the difference between hair and blood based test?

You can't test immune reactions via a hair sample, and in many cases there have been discrepancies in results when parts of the hair have been coloured/bleached. This has led to inconsistency in the sample tested twice. Our IgG 1,2,3,4 blood based testing covers the full range of antibodies responses, this is important, if a particular food elevates any antibodies against it, this means your gut and immune system recognises that food as a threat. This could affect the nutrients absorbed from this particular food and leads to multiple symptoms.

Do high IgG antibody levels cause symptoms?

When a food causes the body to produce high levels of IgG then these antibodies combine with the protein in the food to form an ‘antigen-antibody complex’. These complexes are usually eliminated by other cells in the immune system. However, if the immune system is overloaded, these insoluble molecules become deposited in tissues within the body, causing chronic inflammation and the subsequent production of symptoms.

Why test for IgG antibodies to foods?

The efficacy of a diet based on the measurement of IgG antibodies specific for food components has been demonstrated in a number of conditions, both in independent studies and clinical practice. Excellent results have been obtained in patients with migraine, IBS and obesity.

What is the lower age limit for testing?

Supply Life's existing policy for a lower age limit on testing for IgG food antibodies is that we do not recommend testing on children under the age of 2 years. We base this on the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the Diagnosis of Coeliac Disease 2012, which states that there is a possibility of false negative results occurring in infants younger than 2 years of age. This related to the fact that the infant gut is more permeable than that of an adult coupled with immature mucosal immunity that is still in the learning and development stage. We have used this criterion as antibody measurements in Coeliac Disease are comparable to food IgG measurements used in our food intolerance tests. However, we are aware that there are in fact no published guidelines that specifically indicate a minimum age for testing for such IgG antibodies, for example the guidelines for testing for coeliac antibodies indicate that such testing can be performed any time after the introduction of gluten into the diet. Therefore, where such requests are received from a statutory regulated professional the decision of when and what tests to perform will remain the responsibility of the requesting clinician.

What should be considered before testing - Is there any medication that I should avoid when taking a food intolerance test, due to its potential effects upon the results?

Customers should avoid the use of immunosuppressant medication if possible if performing these tests, as they may have an impact upon the results. Please refer to the medication datasheet in the “Support” section for further details.

How does the test work?

Food extracts are 'printed' onto nitrocellulose 'pads'™ on a glass microscope slide, together with calibration standards and controls. A blood sample provided by the patient is diluted and dispensed onto each printed microarray. Food IgG antibodies, if present, bind to the food extracts and the results are measured by a high-resolution scanner, before being calibrated against the standards using the reporting software to give quantitative results. This software then produces a tailor-made printout of the final food IgG antibody result for each food on the requested food panel.

Do you need to full the microvette all the way to the white line?

Although it is advisable to completely fill the tube, a half filled microvette tube should be enough to run the test. If there are any problems with a sample and the lab will let the customer know. However, if you are ordering two tests we can test from one sample if you provide a full microvette.

Do you need to store the blood in the fridge, if not sending the same day?

Yes, it does need to be stored in the fridge with the lid secured if not sending on the same day.

Can I upgrade my test to a larger food panel?

You can upgrade for up to a maximum of 4 weeks from the date that your first sample is received.

What are the sample requirements and test turnaround?

A pin-prick blood sample is required. Results are available within 10 working days.

Does the Supply Life test for all subclasses of IgG antibody or only IgG4?

Our process screens for all IgG subclasses 1-4, with the numbers on the test report representing the total IgG concentration for each food extract in the selected panel.

The Vital Link Between Eating Well and Sleeping Well: Navigating Food Intolerances for Optimal Sleep Patterns

August 7, 2023

The intricate dance between eating and sleeping has long been acknowledged as crucial for maintaining overall well-being. Our daily habits, including dietary choices, have a profound impact on the quality and duration of our sleep. While many factors influence our sleep patterns, one that is often overlooked is the role of food intolerances. Emerging research suggests that avoiding food intolerances can significantly enhance sleep quality and duration, shedding light on the intricate relationship between our digestive system and our sleep cycles.

The Connection: Eating Well and Sleeping Well

It's no secret that consuming a well-balanced diet rich in nutrients is essential for promoting physical and mental health. A diet that prioritises whole foods, including fruits, vegetables, lean proteins, and whole grains, can positively influence various bodily functions, including those that regulate sleep. This connection lies in the interplay between certain nutrients and their effects on neurotransmitters that govern sleep, such as serotonin and melatonin.

Serotonin, often referred to as the "feel-good" neurotransmitter, is crucial in regulating mood and sleep-wake cycles. It is derived from the amino acid tryptophan, which is commonly found in protein-rich foods. A balanced diet ensures an adequate intake of tryptophan, which can contribute to the production of serotonin and, consequently, better sleep quality.

Furthermore, melatonin, often referred to as the "sleep hormone," plays a pivotal role in signalling to our body that it's time to wind down and prepare for sleep. Melatonin synthesis is influenced by the amino acid precursor tryptophan and certain vitamins and minerals, such as vitamin B6, magnesium, and zinc, which are often found in a diverse and nutrient-rich diet.

Food Intolerances and Sleep Disruption

However, the connection between eating well and sleeping well becomes more complex when food intolerances are introduced into the equation. Food intolerances occur when the body has difficulty digesting certain foods or components, often leading to gastrointestinal discomfort. The discomfort and inflammation caused by these intolerances can have far-reaching effects, including disturbances in sleep patterns.

One notable example is lactose intolerance, a condition in which the body lacks the enzyme lactase required to digest lactose, the sugar found in dairy products. Consuming dairy products for individuals who are lactose intolerant can lead to bloating, cramping, and other digestive issues that might interfere with sleep comfort and quality.

Another potential culprit is gluten intolerance, often seen in individuals with celiac disease or non-celiac gluten sensitivity. Inflammation triggered by gluten consumption can lead to discomfort and gastrointestinal distress, which in turn disrupts sleep patterns.

Identifying and managing food intolerances can play a crucial role in improving sleep quality. If you suspect that certain foods are affecting your sleep, consider these steps:

Maintain a Food Journal: Keep track of what you eat and when you experience sleep disturbances. This can help you identify potential correlations between specific foods and disrupted sleep patterns.
Experiment with Elimination: Under the guidance of a healthcare professional, try eliminating suspected trigger foods from your diet for a period and observe any changes in sleep quality and digestive comfort.
Take a Home Food Intolerance Test: If you suspect food intolerances are affecting your sleep, purchase a home food intolerance test and start to take your health into your own hands!

Compare home food intolerance tests today and purchase a kit that best suits you.

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